Antioxidant Properties of Some Caucasian Medicinal Plants

Authors

  • Giovanni N. Roviello Institute of Biostructures and Bioimaging, Italian National Council for Research (IBB-CNR), Naples, Italy Author
  • Valentina Mittova Teaching University Geomedi, Tbilisi, Georgia Author https://orcid.org/0000-0002-9844-8684
  • Zurab R. Tsetskhladze Teaching University Geomedi, Tbilisi, Georgia Author https://orcid.org/0000-0003-0774-0020
  • Roza Bidzinashvili National Botanical Garden of Georgia, Tbilisi, Georgia Author
  • Marina Berdzenishvili Green movement of Georgia, Tbilisi, Georgia Author
  • Malkhaz Vakhania Teaching University Geomedi, Tbilisi, Georgia Author
  • Tornike Mindiashvili Teaching University Geomedi, Tbilisi, Georgia Author
  • Mariam Kobiashvili Teaching University Geomedi, Tbilisi, Georgia Author

DOI:

https://doi.org/10.56580/GEOMEDI44

Keywords:

Symphytum caucasicum M. Bieb., Thymus tiflisiensis Klokov & Des.-Shost., Paeonia daurica subsp. mlokosewitschii (Lomakin) D. Y. Hong, Cyclamen coum Mill., antioxidant activity, DPPH assay, medicinal use

Abstract

Since antioxidants may be implicated in disease-related processes, studying these molecules is crucial. The detection of new antioxidants may result in the application of these compounds as medications. Mountain systems and long-term climate changes have contributed to the development of the Caucasus biodiversity hotspot, characterized by a great variety of plant species. For centuries many Caucasian plants were used for the treatment of different diseases, however, the scientific knowledge of the composition of natural drugs is still far from exhaustive. The present review indicates that Caucasian medicinal plants Symphytum caucasicum M. Bieb., Thymus tiflisiensis Klokov & Des.-Shost., Paeonia daurica subsp. mlokosewitschii (Lomakin) D. Y. Hong, and Cyclamen coum Mill. are a valuable source of antioxidants, and extracts of these plants exhibit significant total antioxidant activity. Various classes of antioxidants were revealed in the aerial part and roots of Symphytum caucasicum” M. Bieb., tubers of Cyclamen coum Mill., petals of Paeonia daurica subsp. mlokosewitschii (Lomakin) D. Y. Hong, and the aerial part of Thymus tiflisiensis Klokov & Des.-Shost. These compounds included phenolic compounds, water-soluble antioxidants, alkaloids, terpenes, and saponins. In vitro studies demonstrated that these antioxidants are beneficial in suppressing some biological effects related to multiple diseases. The review demonstrates the benefits of using Caucasian medicinal plants for the treatment of different disorders and offers information to scientists who are working to produce safe plant-based medications.

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References

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Published

2024-06-26

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How to Cite

1.
Roviello GN, Mittova V, Tsetskhladze ZR, et al. Antioxidant Properties of Some Caucasian Medicinal Plants. MIMM. 2024;27(1). doi:10.56580/GEOMEDI44

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